Acronym CHITOWOUND
Category
Seafood Processing
Title Biological Tools Implementation for New Wound Healing Applications of Byproducts from the Crustacean Seafood Processing Industry Programme International Cooperation
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National-European Coordinator Kjell Morten Varum Coordinator email NA
Coordinator institution
NTNU - Norwegian University of Science and Technology (Norway)
Institutions involved
FORTH - Foundation for Research and Technology Hellas (Greece) ,
NA - SINTEF Energy Research (Norway) ,
TLU - Tallinn University (Estonia) ,
UVT - West University of Timisoara (Romania) ,
Start year 2017 End year 2019 Funding (€) € 884,000 Website http://chitowound.elearning-chemistry.ro/project/ Summary The aim of the project is to develop an efficient process that can be upscaled for isolation of chitin and protein/peptides from crustacean waste in a more environmentally friendly than the current technology. Additional advantageous are increased quality and reproducibility of the chitin and thereby the chitosan products, as well as potential for utilizing the protein fraction present in this abundant marine biomass. Two chitosans of widely varying degree of deacetylation (DD) will be targeted for their biodegrability and wound healing applications.
The objectives of Chitowound are as follows:
1. To increase the quality and reproducibility of chitin from crustacean waste by development of processing steps utilizing non-destructive enzymatic treatment of the biomass. Specifically, proteases with low pH optimum will be used in the acidic demineralization step to facilitate matrix opening and ease subsequent deproteinization.
2. To characterize the isolated protein/peptide fraction and explore potential use of this as a media component for microbial cultivation and for bioactive properties
3. To produce large batches of chitosans with widely different chemical composition; one with DD of 80-90 (present commercial qualities) and a new chitosan not commercially available with DD of 50% being soluble at physiological pH and with very different biodegradabily.
4. To increase functionality and value of these chitosans by peptide modifications
5. To use the functionalized chitosans for creating new biomaterials targeted for wound healing applications, including also the preparation of new chitosan-based biomaterials
Keywords
Wastes;
Protein;
Waste valorization;
Shellfish;
Biomaterial;
Bioprospecting;
Bioactive compounds;
Crustacean;
Marine Region
76
Not associated to marine areas
0
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