Acronym NA
Category
Aquaculture
Title Challenges towards sustainable aquafeeds-plant nutrients and contaminants interactions-Use of biological models and indicators- Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Marc H. G. Berntssen Coordinator email marc.berntssen@nutr.fiskeridir.no
Coordinator institution
NIFES - National Institute of Nutrition and Seafood Research (Norway)
Institutions involved
NA
Start year 2010 End year 2015 Funding (€) € 2,457,606 Website https://prosjektbanken.forskningsradet.no/project/FORISS/200506?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=0&ProgAkt.3=SIPHINIFES-SIP%20ved%20HI Summary The limited access to fish meal and fish oil for the rapidly growing aquaculture has led to the replacement of fish meal and oil with plant ingredients over the last decade. This has reduced the level of notorious contaminants (eg dioxins), however, has also introduced new chemical contaminants (eg PAHs and pesticides) that are normally not associated with salmon farming. The use of plant ingredients has also altered the nutrient profile (fatty acid antioxidants). Nutrients are well known to interact and even protect against contaminant toxicity. The increased replacement of marine ingredients with plant ingredients has increased the need for knowledge of new nutrients and contaminants and especially on their interaction and common biological outcome. Nutrient-contaminant interactions can occur at several levels of biological organization including intestinal uptake, peripheral distribution, and / or central cellular pathways. The multitude of possible nutrient-contaminant combinations as well as inter actions points at cellular pathways requires an initial cytotoxic screening and marker identification, before studying cellular mechanisms of interaction or in vivo target animal evaluation. The present project aims to elucidate on the interactions of pla nt ingredient related contaminants and nutrients on dietary uptake, metabolism, and neurodevelopment related to novel aquafeed, with emphasis on generating basic knowledge on the combined effect by use of biological indicators in model systems at different levels of biological organization and / or central cellular pathways. The multitude of possible nutrient-contaminant combinations as well as inter actions points at cellular pathways requires an initial cytotoxic screening and marker identification, before studying cellular mechanisms of interaction or in vivo target animal evaluation. The present project aims to elucidate on the interactions of plant ingredient related contaminants and nutrients on dietary uptake, metabolism, and neurodevelopment related to novel aquafeed, with emphasis on generating basic knowledge on the combined effect by use of biological indicators in model systems at differen t levels of biological organization and / or central cellular pathways. The multitude of possible nutrient-contaminant combinations as well as inter actions points at cellular pathways requires an initial cytotoxic screening and marker identification, before studying cellular mechanisms of interaction or in vivo target animal evaluation.
Keywords
Fish health;
Feed composition;
Indicators;
Marine Region
76
Not associated to marine areas
0
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