Acronym NA
Category
Aquaculture
Title Emergence of virulence and antibiotic-resistance vectors in coastal and deep sea marine environments and analysis of the mechanisms and conditions underlying their spread and evolution Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Mikhail Iakimov Coordinator email NA
Coordinator institution
CNR-ISP - National Research Council; Institute of Polar Sciences (Italy)
Institutions involved
CNR-ISMAR - National Research Council; Institute of Marine Sciences (Italy) ,
UNIVPM - Polytechnic University of Marche (Italy) ,
UNIGE - University of Genoa (Italy) ,
Start year 2019 End year 2023 Funding (€) € 499,355 Website NA Summary The project aims at investigating the role of marine environment in the emergence and spread of virulence (VIR) and antibiotic-resistance (AR) genes within microbial communities via human and natural pressure. The study will focus on microbial assemblages thriving in anthropogenically affected coastal areas such as harbours and those in proximity of hospitals and aquacultures, where the load of both pathogens and antibiotics is expected. Natural sediments will be studied by biomolecular means to obtain a wide array of VIR, AR genes and mobile elements. Moreover, specific matrices, such as chitinous and marine plastic debris, which may serve as a protective environment enabling the microorganisms to form biofilms and facilitating their dispersal, will be also studied. Metadata will be utilised to focus on the identification of several transmittable elements as representative targets. Cultural methods will be applied to isolate novel bacterial strains harbouring VIR and AR genes as candidate vehicles within the selected areas. Information deriving from cultivable strains will be further integrated to the diversity profiles based on molecular methods. Chitin and microplastics will be tested at mesocosm scale as biofilm-favouring substrates enhancing genomic exchange events.
Keywords
Microbial communities;
Environmental impact;
Toxic substances;
Anthropic activity;
Impacts;
Genetic;
Human health;
Marine Region
76
Not associated to marine areas
0
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