Acronym NA
Category
Aquaculture
Title Hva betyr ny PD-virusvariant for norsk fiskeoppdrett? Karakterisering av virus, sykdomsutvikling og utbredelse - What does the new PD virus variant mean for Norwegian fish farming? Characterization of viruses, disease development and spread Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Hilde Sindre Coordinator email hilde.sindre@vetinst.no
Coordinator institution
NVI - Norwegian Veterinary Institute (Norway)
Institutions involved
NA - MSD Animal Health Norge AS (Norway) ,
NA - PatoGen Analyze AS (Norway) ,
Start year 2012 End year 2013 Funding (€) € 829,938 Website https://www.fhf.no/prosjekter/prosjektbasen/900799/ Summary Pancreatic disease (PD) in Norway has been shown in several independent studies to be caused by a Norwegian variant of salmonid alphavirus, subtype 3 (= SAV3). In the spring of 2011, PD caused by another variant of SAV was detected for the first time in Norway. This new Norwegian variant is genetically similar to SAV subtype 2 which is the cause of Sleeping Disease in rainbow trout (RØ) in freshwater in Europe. A SAV2-like variant has also been detected in PD outbreaks of salmon in the sea in Scotland. Further studies have shown SAV2-like virus in up to 16 PD cases in 2010–2012. Knowledge about this new virus variant related to PD outbreaks in Norway is limited. In the present project, results from both full-length sequencing and subtyping showed that all marine SAV2 isolates examined in Norway are almost identical, and this indicates a single introduction to Norwegian salmon farming a relatively short time ago. This is supported by the results from the subtyping of older PD outbreaks, where the first discovery of marine SAV2 was in Midsund in June 2010. The virus has then spread locally in the Midsund area and then northwards in 2011–2012. In the old core area for PD (Rogaland, Hordaland and Sogn og Fjordane) only SAV3 is detected. Results from infection trials show higher mortality associated with SAV3 than SAV2 isolates. These results are supported by field data, which also show significantly higher mortality in PD outbreaks caused by SAV3 than SAV2. The infection test shows that both SAV groups give a significant reduction in growth after 12 weeks compared with the control group. However, there is no difference between the SAV groups, and this is in accordance with field data.
Keywords
Disease;
Salmon;
Genetic;
Genomic sequencing;
Fish;
Cage aquaculture;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
