Acronym NA
Category
Aquaculture
Title The physiological function of leptin in salmonids: towards improved feed conversion efficiency and quality traits in aquaculture Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Thrandur Björnsson Coordinator email Thrandur.Bjornsson@bioenv.gu.se
Coordinator institution
UGOT - University of Gothenburg (Sweden)
Institutions involved
NA
Start year 2012 End year 2014 Funding (€) € 612,800 Website NA Summary In livestock production, improved ratio of muscle to fat deposition is known to improve feed conversion, lower production costs and decrease nitrogenous waste excretion. Fat mass and deposition is also recognized as a key to product quality and/or reproductive success. In finfish aquaculture, surprisingly little attention has been paid to links between adiposity, feed conversion and product quality, especially as major challenges facing sustainable aquaculture development concern nitrogenous wastes and usage of feed sources. In mammals, leptin (Lep) is a key endocrine regulator of adiposity, reporting body fat mass to the hypothalamus and other regulatory cells. The responses are decreased appetite and increased pituitary GH secretion, both leading to leaner growth. In fish, data on the physiological function of Lep are still scarce. The recent identification of Lep in fish, and lack of homologous research tools, both stem from a major sequence divergence between fish and mammals. Our on-going Formas project indicates a role for Lep in energy balance, and has provided a broad array of homologous research tools. In vitro and in vivo approaches will be used examining distribution and regulation of Lep secretion, Lep effects on energy metabolism, puberty and GH secretion, the role of binding proteins and receptors. The results will be of fundamental and applied significance, as the focus is on the biological regulation of important production and quality traits.
Keywords
Fish biology;
Fish;
Salmon;
Marine Region
76
Not associated to marine areas
0
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