Acronym NA
Category
Aquaculture
Title Effektive vaksiner og vaksinestrategier for torsk, fokus på bakterielle agens - Effective vaccines and vaccine strategies for cod, focus on bacterial agents Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Kjersti Gravningen Coordinator email kjersti.gravningen@pharmaq.no
Coordinator institution
NA
Institutions involved
NA
Start year 2006 End year 2009 Funding (€) € 109,108 Website https://prosjektbanken.forskningsradet.no/project/FORISS/174220?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=0&Prosjektleder=Anne-Merethe+Hanssen Summary Classical vibriosis is the most serious bacterial disease in cod farming in Norway. Atypical Aeromonas salmonicida is isolated from more and more fry and larger cod farms. As the cod industry grows, we also expect that other known and unknown organisms could cause disease. Moritella viscosa and V. salmonicida are already isolated. Water-based vibriosis vaccines do not provide full protection against vibriosis. Isolated new varieties of Vibrio anguillarum serotype O2a from diseased vaccinated cod and experimental experiments have shown that the vaccine provides little or no protection against two deviating varieties. The significance of these aberrant isolates will be mapped and the need to include these in vaccines (stabs and dips) will be investigated. Atypical A. salmonicida over surface protein, the A protein, which is probably an important protective antigen in the vaccine, varies between isolates from different fish species. These differences may be the reason why the salmon furunculosis vaccine does not protect against the variant of atypical A. salmonicida isolated from diseased cod. Assessment of which isolates may need to be included in a furunculosis vaccine for cod will be considered. New compositions and formulations for dipping and injection vaccines that increase the level and duration of protection against vibriosis and furunculosis will be developed. In the long run, it is likely that cod should be vaccinated with more complex combination vaccines that should also include other agents such as winter sores, cold water vibriosis. The composition of such vaccines will be assessed based on characterization and the vaccines tested in vaccination and infection trials.
The project will deliver concepts for future vaccination of cod.
Keywords
Vaccines development;
Cod;
Genetic;
Fish;
Fish health;
Disease;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
