Acronym FORNY
Category
Aquaculture
Title Novel vaccine for salmon farming Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Aina Haugen Rengmark Coordinator email NA
Coordinator institution
NA
Institutions involved
NA
Start year 2017 End year 2020 Funding (€) € 869,100 Website https://prosjektbanken.forskningsradet.no/en/project/FORISS/267845?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=30&Organisasjon.3=INVEN2+AS Summary "Piscirickettsia salmonis is a bacterium naturally found in all oceans, which can lead to major outbreaks of the salmonid disease Salmonid Rickettsial Septicaemia (SRS). SRS is a growing problem, particularly in the Chilean salmon farming market. Currently, there is no effective treatment or functioning vaccine with sufficient protection to combat SRS. Annual losses were estimated at 6.4 billion NOK in 2015.
Professor Hanne Winther-Larsen's group from UiO has shown that P. salmonis secretes small vesicles (OMVs) from the bacterial surface. The researchers have demonstrated that OMVs given as a vaccine provide good protection against P. salmonis infection in a zebrafish model. The group has also developed a protocol for effectively culturing the bacterium and shown that different geographical strains of the bacterium have varying virulence.
In this FORNY project, in collaboration with industrial partners represented by pharmaceutical companies and fish farmers, we have verified that OMVs have potential in SRS vaccine development. The goal was to develop the leading vaccine on the market against P. salmonis, providing protection throughout the entire farming cycle with OMV as a crucial component. The results showed extended immune response and possibilities for boosting or combining with other SRS vaccines, but the OMV vaccine does not seem to provide sufficient protection against SRS alone.
Achieved effects:
We have achieved good collaboration with Mowi, which provides opportunities for future research projects with the fish farming industry and aquaculture sector.
The existing partnership with our industrial partner and potential buyer of the technology, Vaxxinova, will continue after the project's completion for further exploration of results and, importantly, provide opportunities for new research collaborations.
Findings during the project period will have an impact on future vaccine development, knowledge can be disseminated and optimized. Findings will be important for both industry and basic research."
Keywords
Bacteria;
Salmon;
Vaccines development;
Fish health;
Fish;
Disease;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
