Acronym Multifac
Category
Aquaculture
Title Multifaktorielle sykdommer i norsk lakseoppdrett - Multifactorial diseases in Norwegian salmon farming Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Lill-Heidi Johansen Coordinator email lill-heidi.johansen@nofima.no
Coordinator institution
NOFIMA - Norwegian Institute of Food, Fisheries and Aquaculture Research (Norway)
Institutions involved
NA - AquaGen AS (Norway) ,
NVI - Norwegian Veterinary Institute (Norway) ,
Start year 2011 End year 2015 Funding (€) € 1,063,907 Website https://www.fhf.no/prosjekter/prosjektbasen/900658/ Summary Salmon diseases are caused by a combination of one or more pathogens and factors related to host and environment including environmental stress, rearing conditions, physiological and endocrine changes during smoltification and sexual maturation and unbalanced nutrition. Factors that are involved in development of Atlantic salmon diseases and their relative importance are often unknown, making it difficult to choose optimal measures. IPNV carrier condition is an important risk factor due to risk of reactivation. HSMI outbreaks are often observed in the wake of IPN outbreaks, but it is unclear whether or how the presence of IPN virus may increase the salmon's susceptibility to HSMI. To solve multifactorial disease problems, we need to assess interactions between pathogens and stressors. Our experimental models, in combination with traditional and newly developed high-throughput analytical techniques, bioinformatics tools (functional genomics) and metabolomics, makes it possible to analyse various factors in combination with each other.
Main goal: Increase knowledge on the development of multifactorial diseases; assess effects of different variables and their interactions Sub-goals: (1) Evaluate the effect of different variables (genetic resistance against IPN, IPNV carrier condition, IPN reactivation and vaccination) and their combination on the development of HSMI; (2) Evaluate the effect of QTL for IPN resistance on the development of IPNV carrier condition, reactivation of the virus in post-smolts and susceptibility to HSMI; (3) Demonstrate relationships in the field between IPN-status (QTL +/-hosts, IPNV carrier status, IPNV reactivation) in grow-out salmon in sea water and outbreaks/virus titre of HSMI/PRV; (4) Identify disease markers that can be used by the industry for better evaluation of the health status of the fish.
Keywords
Fish;
Genetic;
Biology;
Disease;
Salmon;
Marine Region
41
Norwegian Sea (27.IIa)
1
Marine Region Map
