Acronym ISA
Category
Marine Biotechnology
Title Application of a new vaccine principle to combat infectious salmon anemia Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Siri Mjaaland Coordinator email siri.mjaaland@vetinst.no
Coordinator institution
NVI - Norwegian Veterinary Institute (Norway)
Institutions involved
UiT - The Arctic University of Norway (Norway) ,
UiO - University of Oslo (Norway) ,
Usach - University of Santiago de Chile (Chile) ,
SDU - University of Southern Denmark (Denmark) ,
Start year 2011 End year 2013 Funding (€) € 665,320 Website https://www.fhf.no/prosjekter/prosjektbasen/900588 Summary "Infectious salmon anemia (ISA) is still a serious viral disease for both the national and the international farmed salmon industry. The ongoing devastating ISA disease outbreaks in Chile, is a reminder of the importance of this emerging disease.
In this project it will investigated whether targeting viral antigen to salmonid APCs can be used to dissect the immune mechanisms important for protection against ISAV, and to develop an effective vaccine against the disease.
The project consists of the following work packages (WPs):
WP1. Development of salmon targeting vaccines: The aim is to construct vaccine candidates targeting salmon APCs and test their functionality and specificity in vitro.
WP2. Experimental trials: The aim is to establish a ""proof of principle"" for targeting DNA vaccines in fish, using ISAV and Atlantic salmon as a model system.
WP3. Host responses: The aim is to study protective humoral and cellular immune responses after vaccination and challenge of Atlantic salmon.
This work has the potential to produce cheap and effective vaccines against infectious salmon anemia. In addition, this tool represents a unique opportunity to provide basal knowledge on humoral and cellular responses to viral infection in Atlantic salmon. In this way the project will benefit both industrial interests and the basic knowledge on fish health, virus-fish interactions and Orthomyxo viruses, which all represent important strategic objectives of the applicant institution."
Keywords
Salmon;
Fish health;
Disease;
Genetic;
Fish;
Vaccines development;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
