Acronym TARGETFISH
Category
Aquaculture
Title Targeted disease prophylaxis in European fish farming Programme FP7
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
FP7 - Collaborative Project targeted to a Special Group (such as SMEs)
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
KBBE – Food, Agriculture and Fisheries, and Biotechnology
Specific Programme (FP7)
Cooperation
Funding source European Coordinator Geert Frits Wiegertjes Coordinator email geert.wiegertjes@wur.nl
Coordinator institution
WUR - Wageningen University and Research (Netherlands)
Institutions involved
UAB - Autonomus University of Barcelona (Spain) ,
NA - Bigdna Ltd (United Kingdom) ,
NA - BioMar (Denmark) ,
NA - Bioorganic Research & Services SA (Spain) ,
NA - Centro Veterinario Y Agricola Ltda (Chile) ,
NA - Danish Aquaculture Association (Denmark) ,
IZSVe - Experimental Zooprophylactic Institute of Venice (Italy) ,
FRS - Fisheries Research Services (United Kingdom) ,
NA - Fishlab (Denmark) ,
INRA - French National Institute for Agricultural Research (France) ,
FLI - Friedrich Loeffler Institut (Germany) ,
HUJI - Hebrew University of Jerusalem (Israel) ,
NA - Ingeniatrics Tecnologias SL (Spain) ,
INIA - National Institute of Agricultural and Food Research and Technology (Spain) ,
NA - Naxo OÜ (Estonia) ,
NVH - Norwegian School of Veterinary Science (Norway) ,
NA - Panagiotis Christofilogiannis-IOANA TAVLA (Greece) ,
NA - PatoGen Analyze AS (Norway) ,
NA - Ridgeway Biologicals Ltd (United Kingdom) ,
NA - Rossi International AS (Denmark) ,
DTU - Technical University of Denmark (Denmark) ,
NA - Tethys Aquaculture Ltd (United Kingdom) ,
UOA - University of Aberdeen (United Kingdom) ,
KU - University of Copenhagen (Denmark) ,
UM - University of Murcia (Spain) ,
UoS - University of Stirling (United Kingdom) ,
UNITUS - University of Tuscia (Italy) ,
VRI - Veterinary Research Institute (Czech Republic) ,
W42 - W42 Industrial Biotechnology GmbH (Germany) ,
Start year 2012 End year 2017 Funding (€) € 8,674,454 Website http://targetfish.eu/project Summary European aquaculture production provides direct employment to 65.000 people with a turnover of E3 billion. However, the lack of authorised veterinary medicinal products and the consequent disease outbreaks in farmed fish species costs the sector 20% of the production value. The most appropriate method for disease control, both on economical and ethical grounds, is disease prevention by vaccination. TargetFish will advance the development of existing (but currently sub-optimal) and new prototype vaccines against socio-economically important viral or bacterial pathogens of Atlantic salmon, rainbow trout, common carp, sea bass, sea bream and turbot. The project will develop targeted vaccination strategies for currently sub-optimal and for novel vaccines. Improved vaccines will be brought closer to industrial application by addressing practical issues such as efficacy, safety and delivery route. TargetFish will also establish a knowledge- and technology-base for rational development of next generation fish vaccines. To achieve these challenging tasks, we brought together 29 partners from 11 EU member states, 2 associated countries and 1 International Cooperation Partner Country (ICPC). In this large multidisciplinary consortium an approximate equal number of RTD and SME partners will cooperate closely while keeping an intensive communication with the large vaccine and nutrition industries via an Industry Forum. Specifically, TargetFish will: (1) Generate knowledge by studying antigens and adjuvants for mucosal routes of administration while analysing the underpinning protective immune mechanisms; (2) Validate this knowledge with response assays for monitoring vaccine efficacy and study safety aspects, including those associated with DNA vaccines; (3) Approach implementation of prototype vaccines by optimizing vaccination strategies thus; (4) Shortening the route to exploitation. Thereby, this project will greatly enhance targeted disease prophylaxis in European fish farming.
(1) To generate a knowledge- and technology-base for rational development of next generation fish vaccines by studying antigens and adjuvants for mucosal routes of administration; (2) To validate knowledge of immune responses for monitoring vaccine efficacy and safety, including issues associated with DNA vaccines; (3) To approach implementation of prototype vaccines by optimizing vaccination strategies, thus shortening the route to exploitation.
Keywords
Trout;
Vaccines development;
Seabass;
Fish;
Engineering;
Disease;
Turbot;
Fish biology;
Seabream;
Genetic;
Flatfish;
Salmon;
Carp;
Fish health;
Marine Region
62
Aegean Sea (GSA 22)
50
Sardinia (east) (GSA 11.2)
65
North Levant (GSA 24)
46
Corsica Island (GSA 8)
48
South Tyrrhenian Sea (GSA 10)
52
Northern Alboran Sea (GSA 1)
47
Ligurian and North Tyrrhenian Sea (GSA 9)
54
Balearic Island (GSA 5)
64
Crete Island (GSA 23)
58
Southern Ionian Sea (GSA 21)
74
Northern Adriatic (GSA 17)
51
Sardinia (west) (GSA 11.1)
71
South of Sicily (GSA 16)
26
Northwest Coast of Scotland and North Ireland (27.VIa)
61
Eastern Ionian Sea (GSA 20)
45
Southern Adriatic Sea (GSA 18)
56
Alboran Island (GSA 2)
57
Southern Alboran Sea (GSA 3)
68
South Levant (GSA 26)
53
Northern Spain (GSA 6)
60
Western Ionian Sea (GSA 19)
49
Gulf of Lions (GSA 7)
66
Cyprus Island (GSA 25)
75
Northern Tunisia (GSA 12)
70
Malta Island (GSA 15)
69
Gulf of Gabes (GSA 14)
55
Algeria (GSA 4)
67
Levant (GSA 27)
72
Gulf of Hammamet (GSA 13)
29
Marine Region Map
