Acronym NA
Category
Aquaculture
Title Proteínas y péptidos alimentarios como antivirales de interés en Acuicultura - Food proteins and peptides as antivirals of interest in Aquaculture Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator M. Carmen Sarasquete Coordinator email carmen.sarasquete@icman.csic.es
Coordinator institution
CSIC-ICMAN - Spanish National Research Council; Institute of Marine Science of Andalucía (Spain)
Institutions involved
NA
Start year 2005 End year 2007 Funding (€) € NA Website NA Summary It has been shown that several food proteins and peptide derivatives can have various physiological functions in the organism, for example as opiates, antihypertensive agents, immunomodulators, antimicrobial agents etc. Previous results of the research group of I. Recio and M. Ramos of the Instituto de Fermentaciones Industriales of the CSIC, have concluded that milk and egg proteins are excellent substrates to produce bioactive peptides with antioxidant and antihypertensive activity. The employment of food peptides and proteins as antimicrobial agents in other applications has awoken great interest because of the harmless nature of these compounds. Recently, explorations have begun into the possible antiviral activity of different fragments derived from milk products against some mammal viruses. Similarly, chemically changed food proteins, such as lactoferrin, in which the surface charge of the protein is altered, have been shown to present a clear activity against type 1 human immunodeficiency virus. However, there are no data on the activity of food proteins and peptides against viruses that cause diseases in fish. Owing to the intensification and diversification of aquaculture worldwide, there is increasing interest in viruses that affect teleost species, both as a study model and also for potential practical applications. These viruses constitute an innovative model to determine the biological activity of food peptides and proteins that could present antiviral or immunostimulant characteristics and could be used in medicinal products or coadjuvants of DNA vaccines. To date, the application of potential antiviral agents in edible fish has not been developed, since these are toxic molecules, or ones of high cost or low activity. However, the proteins or peptides studied in this project are derived from food products, making them suitable for use in edible fish. Moreover, if they prove to be sufficiently active they can be produced at low cost.
Keywords
Animal welfare;
Protein;
Fish health;
Bioprospecting;
Fish;
Bioactive compounds;
Marine Region
76
Not associated to marine areas
0
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