Acronym NA
Category
Marine Biotechnology
Title Tenacibaculum spp. causing ulcers in farmed Atlantic salmon Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Henrik Duesund Coordinator email NA
Coordinator institution
NA
Institutions involved
NA
Start year 2014 End year 2018 Funding (€) € 179,400 Website https://prosjektbanken.forskningsradet.no/project/FORISS/241364?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=960&Departement=Landbruks-+og+matdepartementet&source=FORISS&projectId=296413 Summary Skin ulcers have been a major disease problem in the production of Atlantic salmon in Norway. Cermaq has experienced high mortality and downgrading at harvest due to Tenacibaculum spp. Infections. There is little public research on this topic, so Cermaq established a research project in 2013 to build knowledge about Tenacibaculum spp. Infections, and to develop preventative measures. This project included two master thesis studies at the University of Bergen. The preliminary findings in these studies sho wed by a pilot challenge study, that we were able to reproduce the disease seen in the field. In addition this pilot study showed indications of a new species in the genus Tenacibaculum, that needs to be described. The main goal of this project "Tenaciba culum spp. Causing ulcers in farmed Atlantic salmon" is to gain more knowledge about Tenacibaculum spp. and infections with this bacterium and develop preventive measures to reduce impact in salmon farming. This will be done by standardizing the infection model to be able to do vaccine tests and measure antibody response in infected fish to see if vaccination could be a solution. The bacteria will also be described as a species using traditional methods, but in addition a full genome sequence has and will be used to look at Multi Locus Sequence Typing (MLST) and Various Number of Tandem Repeats (vNTR). An antibody response test will be carried out by developing a low tech vaccine candidate and running a vaccine trial. This will allow us to investigate if a vaccine could be solution in the future. It will also be important to attempt to find the marine reservoir of the bacteria and try to find the infection routs. This will be done by using a real time RT-PCR assay developed in the pilot study. The knowled ge obtained in the characterization will be important in this work.
Keywords
Genomic sequencing;
Bacteria;
Disease;
Vaccines development;
Fish;
Genetic;
Salmon;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
