Acronym ViVaFish
Category
Marine Biotechnology
Title Fish Virus Vaccines Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Espen Rimstad Coordinator email espen.rimstad@nmbu.no
Coordinator institution
NMBU - Norwegian University of Life Sciences (Norway)
Institutions involved
IMR - Institute of Marine Research (Norway) ,
NVI - Norwegian Veterinary Institute (Norway) ,
UiT - The Arctic University of Norway (Norway) ,
Start year 2014 End year 2018 Funding (€) € 505,263 Website https://www.nmbu.no/en/projects/node/27880 Summary In the Viva Fish (Fish Virus Vaccines) platform project, we aim to generate knowledge, tools and methods that will contribute to better vaccines against viral diseases in farmed fish. The viral diseases we focus on are Pancreas disease (PD), Heart and skeletal muscle inflammation (HSMI), Cardiomyopathy (CMS) and Infectious salmon anemia (ISA).
Some subgoals:
Identification of specific functions of virus proteins and genomic structures important for vaccine development, and development of live attenuated and replicon vaccines
Identification of host proteins involved in the binding and entry of viruses.
Determine the effect of IFN as adjuvant in the adaptive immune response of Atlantic salmon against different virus proteins.
Determine mRNA signatures of protective responses by transcriptome analysis of tissue after administration of virus protein and/or IFN- and/or virus protein- expressing plasmids.
Analysing CTL activity in muscle following DNA vaccination.
Characterization of available anti-salmon Abs and development of new reagents for immunophenotyping of B- and T- cells, and immune response monitoring.
Characterization of short and long term B-cell responses induced by vaccination.
Develop assays to better understand B-cell responses.
Optimization of delivery systems
Assays for long-lasting antiviral immunity
Keywords
Vaccines development;
Salmon;
Fish health;
Genetic;
Fish;
Disease;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
