Acronym HTSAME
Category
Fisheries
Title High Throughput SNP Analysis in the Marine Environment Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Paulo Prodohl Coordinator email NA
Coordinator institution
QUB - Queen's University Belfast (United Kingdom)
Institutions involved
NA
Start year 2017 End year 2018 Funding (€) € 125,555 Website NA Summary Recent improvements in the speed, cost and accuracy of next generation sequencing (NGS) and associated development in the accompanying bioinformatics pipelines, are providing unprecedented new opportunities for high-resolution population studies in the Marine environment. Of particular relevance, within this context are Single Nucleotide Polymorphisms (SNPs). SNPs are very attractive genetic markers for a number of reasons. Their limited information content (i.e. polymorphism) per locus, is compensated for by their increased number and broad genomic distribution. They are associated with low scoring error; protocols can be easily shared among laboratories, and they are highly amenable to automation. More significantly, they can be identified in terms of adaptive and/or neutral variation. Thus, panels of SNP markers can be selected to address very specific questions related, for instance, to population connectivity and demography or to adaptive response of populations to environmental change (natural or anthropogenically mediated). SNP genotyping costs, for population base studies, however, is still expensive and, thus, beyond the reach of many research groups. In this proposal, we aim to implement analytical capacity for the analysis of 50-200 SNPs for a large number of samples (e.g. 1,000 to 10,000) using a fast and cost effective approach, capitalising on existent genomics infrastructure within the Genomics CTU at QUB. It is anticipated that such high throughput capacity will be available also to other institutions in Ireland through the QUB Genomics CTU.
Keywords
Genomic sequencing;
Genetic;
Population dynamic;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
