Acronym NA
Category
Marine Biotechnology
Title Characterization, fractionation and digestion of oil from Calanus finmarchicus
Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National
Coordinator Kurt Tande
Coordinator email Kurt.Tande@uin.no
Coordinator institution
UIN - Nord University (Norway)
Institutions involved
NA
Start year 2011
End year 2014
Funding (€) € NA
Website https://prosjektbanken.forskningsradet.no/en/project/FORISS/209998?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=450&ProgAkt.3=NAERINGSPH-N%C3%A6rings-phd
Summary "Historical use of wax ester in human consumption indicates that the oil gives favourable health effect in humans which cannot be ascribed to EPA and DHA alone.
The bioavailability of Calanus Oil and the partitioning of components from the oil into body organs have been studied in rodents. The animals were able to hydrolyze wax esters and absorb the fatty acids, since the fatty acid composition of the adipose tissue and liver reflected those being added via the Calanus oil. The composition of the liver lipids demonstrated elongation and desaturation of the C18 omega?3 fatty acids from the feed and accumulation of longer chained omega?3 fatty acids. Elevated levels of FFA and FAOH in the feces suggest that the absorption process, not the hydrolysis, could be a rate limiting step in utilization of small amounts of wax esters included in high fat diets in mice. Additional studies have been performed to demonstrate the digestion of Calanus Oil using in vitro models. The results confirm that Calanus Oil is digested in a similar rate as ethyl esters from fish oil. The digestion rate is slower than that obtained from hydrolysis of triglycerides. Qualitative and quantitative data are obtained using HPLC, solid phase extraction (SPE) and gas chromatography (GC), all tailored for application on Calanus Oil. Three peer reviewed papers have been developed from this project so far."
Keywords
Human health;
Fish oil replacement;
Bioprospecting;
Zooplankton;
Bioactive compounds;
Nutraceutical substances;
Marine Region
42
Barents Sea (27.I)
41
Norwegian Sea (27.IIa)
2
Marine Region Map