Acronym NA
Category
Marine Biotechnology
Title Development of marine functional food to support muscle health and healthy aging in older adults Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator NA Coordinator email NA
Coordinator institution
BII - Bio-marine Ingredients Ireland Ltd (Ireland)
Institutions involved
NA
Start year 2019 End year 2021 Funding (€) € 200,000 Website NA Summary Hydrolysed protein generated from the enzymatic hydrolysis of whole blue whiting fish by BII has high biological value and a favourable amino acid profile. This project aims to evaluate the potential of soluble fish protein hydrolysate (BII-SPH) as a functional food for healthy aging i.e. in an elderly adult cohort to support skeletal health assessed by muscle mass and function in response to exercise training. Through cell-based bioassays and two human trials including an exercise intervention study, a scientific evidence base will be generated towards the application of blue-whiting fish protein hydrolysates to older adults to optimise skeletal muscle health and function. The research will be conducted at three locations in an integrated manner. The project will be co-ordinated by BII. Trials will be conducted at BII plant to produce SPH with improved biological value and enriched leucine content, the key determinants of the efficacy of supplemental protein in supporting muscle health. At UL, potential translational markers of protein anabolism in skeletal muscle cells will be evaluated using a novel, recently validated ex vivo-in vitro cell culture platform with serum conditioned by in vivo feeding of BII-SPH. At DCU, a functional food supplement developed by BII using BII-SPH will have sensory qualities assessed, after which the plasma amino acid kinetics of BII-SPH in older adults will be established and compared to the industry benchmark, whey protein concentrate. Also at DCU, a human intervention study will be conducted on medically-stable older adults (>65 y) undertaking exercise training while supplementing with BII-SPH to assess impact on adaptation to training (muscle mass, physical function and biochemical parameters) compared to isonitrogenous and whey-supplemented conditions.
Keywords
Fish;
Bioprospecting;
Human food;
Protein source;
Blue whiting;
Protein;
Human health;
Marine Region
76
Not associated to marine areas
0
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