Acronym MAMBA
Category
Marine Biotechnology
Title Marine metagenomics for new biotechnological applications
Programme FP7
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
FP7 - Small or Medium-Scale Focused Research Project
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
KBBE – Food, Agriculture and Fisheries, and Biotechnology
Specific Programme (FP7)
Cooperation
Funding source European
Coordinator Peter Golyshin
Coordinator email p.golyshin@bangor.ac.uk
Coordinator institution
NA
Institutions involved
NA - Evoxx Technologies Gmbh (Germany) ,
NA - GCE Blue Maritime Cluster (Norway) ,
HHU - Heinrich Heine University Düsseldorf (Germany) ,
MPIMM - Max Planck Institute for Marine Microbiology (Germany) ,
CNR - National Research Council (Italy) ,
NA - Pharma Mar SA (Spain) ,
NA - Pierre Fabre Research Institute (France) ,
CSIC - Spanish National Research Council (Spain) ,
U of T - University of Toronto (Canada) ,
UBO - University of Western Brittany (France) ,
Start year 2009
End year 2013
Funding (€) € 4,978,203
Website https://cordis.europa.eu/project/id/226977
Summary Marine Metagenomics for new biotechnological applications (MAMBA) is a Collaborative Project, funded by EU within the FP7 program [1]. The MAMBA consortium is built on the expertise of biochemists, geneticists, microbiologists, pharmaceutical chemists and process engineers from the academia. It also involves three companies dealing with synthesis of fine chemicals and biocatalysis and bioprospecting for anti-cancer and anti-ageing agents. The project is focused on a search and use of new microorganisms-derived activities from marine environments that are difficult to access, populated by complex microbial consortia with culturable and unculturable bacterial and archaeal members and characterized by extreme values of hypersalinities, high/low temperatures, high pressure and other parameters. A number of different samples from various sites of Mediterranean Sea and other marine environments have been conducted for the preparation of small, medium and large-insert metagenomic libraries, furthermore more 1.1 thousand positive fosmids and phagemids have been selected after enzymatic screenings of interest with a number of most interesting items fully characterized. The presentation will summarize the major achievements, point at the bottlenecks and show possible pathways of impact of this multinational collaboration beyond the end of the Project.
Keywords
Genomic and gene mining;
Bioprospecting;
Human health;
Marine enzymes;
Microbial communities;
Metagenomic;
Drug discovery;
Marine Region
51
Sardinia (west) (GSA 11.1)
53
Northern Spain (GSA 6)
46
Corsica Island (GSA 8)
59
Black Sea (GSA 29)
47
Ligurian and North Tyrrhenian Sea (GSA 9)
65
North Levant (GSA 24)
60
Western Ionian Sea (GSA 19)
55
Algeria (GSA 4)
58
Southern Ionian Sea (GSA 21)
73
Azov Sea (GSA 30)
62
Aegean Sea (GSA 22)
71
South of Sicily (GSA 16)
56
Alboran Island (GSA 2)
69
Gulf of Gabes (GSA 14)
70
Malta Island (GSA 15)
45
Southern Adriatic Sea (GSA 18)
68
South Levant (GSA 26)
64
Crete Island (GSA 23)
67
Levant (GSA 27)
52
Northern Alboran Sea (GSA 1)
48
South Tyrrhenian Sea (GSA 10)
61
Eastern Ionian Sea (GSA 20)
50
Sardinia (east) (GSA 11.2)
75
Northern Tunisia (GSA 12)
74
Northern Adriatic (GSA 17)
66
Cyprus Island (GSA 25)
54
Balearic Island (GSA 5)
72
Gulf of Hammamet (GSA 13)
63
Marmara Sea (GSA 28)
49
Gulf of Lions (GSA 7)
57
Southern Alboran Sea (GSA 3)
31
Marine Region Map