Acronym GRAPTADIAZONICS
Category
Marine Biotechnology
Title High performance graphene-based aptasensors through versatile diazonium chemistry for detection of food contaminants Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Luisa Plan Coordinator email NA
Coordinator institution
NA
Institutions involved
NA
Start year 2021 End year 2023 Funding (€) € 250,634 Website https://sites.google.com/view/graptadiazonics Summary Ensuring the safety and quality of the food is a global problem deserving great attention. Food contamination with different toxic substances has been shown to induce a multitude of adverse effects for human health. Many research studies are currently attempting to develop accurate, rapid, easy-to-use, disposable and low-cost biosensors for food safety applications. For such applications, graphene proves to be an excellent transducer material, and the progress made towards its functionalization leds to successful interfacing with biomolecules. Although the integration of nanomaterials into the construction of sensors has clear advantages, the main challenges are still around ensuring the stability and the fabrication reproducibility of sensing devices. On the other hand, the proper selection of the biorecognition molecules can improve the selectivity in analysis. Nucleic acid aptamers can have extremely high binding affinity to a variety of target molecules, possess superior chemical stability and are available at reasonable prices. The project aims to bring innovation in the design of the graphene-based aptasensors for food safety by applying the versatile method of diazonium chemistry to effectively interface graphene electrode with the biorecognition layer in order to provide surface-confined aptamers with stability and accessibility for the target, while minimizing non-specific adsorption. An approach towards point of care detection of food contaminants is envisaged.
Keywords
Technology;
Food safety;
Monitoring;
Biosensors;
Toxic substances;
Marine Region
76
Not associated to marine areas
0
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