The available database comprises research projects in Fisheries, Aquaculture, Seafood Processing and Marine Biotechnology active in the time period 2003-2022.
BlueBio is an ERA-NET COFUND created to directly identify new and improve existing ways of bringing bio-based products and services to the market and find new ways of creating value from in the blue bioeconomy.

More information on the BlueBio project and participating funding organizations is available on the BlueBio website: www.bluebioeconomy.eu

Last Update: 2024/06/19

NA
Marine Biotechnology
Potent and selective protein kinase inhibitors from the sea
National Programme
National
Espen Hansen
NA
UiT - The Arctic University of Norway (Norway)
NA
2015
2017
€ 907,080
https://prosjektbanken.forskningsradet.no/en/project/FORISS/244264?Kilde=EU&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=0&Organisasjon.3=PRESS+-+REDD+BARNA+UNGDOM
"MabCent, a center for research-based innovation (CRI) of marine bioactives and drug discovery hosted by UiT The Arctic University of Norway, has since 2007 included protein kinase inhibition assays in its screening campaign of marine extracts. Through the MabCent screening we have identified several marine natural products that inhibit the activity of kinases relevant for treatment of cancer. We have now identified a family of novel compounds with IC50-values in the nM range against a set of kinases that we want to pursue. Based on the data we have generated so far we are seeking funding for a project aimed at advancing these novel kinase inhibitors further through the biodiscovery pipeline with the ultimate goal to identify lead compounds for further drug development. This will be achieved through three work packages: 1) Assessment of biological activity through in vitro and in vivo models. 2) Optimization of biological activity through chemical synthesis. 3) Early toxicity profiling through in vitro and in vivo models."
Bioprospecting; Bioactive compounds; Drug discovery; Human health;
Not associated to marine areas
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