Acronym SECRETed
Category
Marine Biotechnology
Title Sustainable Exploitation of bio-based Compounds Revealed and Engineered from naTural sources
Programme H2020
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source European
Coordinator Manuel Salvador de Lara
Coordinator email manuel.salvador@idener.es
Coordinator institution
NA
Institutions involved
NA - Accuplex Diagnostics Ltd (Ireland) ,
NA - Bio Base Europe Pilot Plant (Belgium) ,
NA - Blue Sinergy SL (Spain) ,
NA - Eberhard Karls University of Tubingen (Germany) ,
NA - EXELISIS PC (Greece) ,
IC - Imperial College London (United Kingdom) ,
ULUND - Lund University (Sweden) ,
MATIS - Matis Ltd (Iceland) ,
NKUA - National and Kapodistrian University of Athens (Greece) ,
NA - Pharma Mar SA (Spain) ,
SE - Sphera Encapsulation Srl (Italy) ,
SZN - Stazione Zoologica Anton Dohrn (Italy) ,
SYL - Sylentis (Spain) ,
USE - University of Seville (Spain) ,
Start year 2021
End year 2025
Funding (€) € 7,787,819
Website https://www.secreted.eu/
Summary The SECRETed project will fully exploit the potential of Systems and Synthetic Biology toolboxes and their application within aquatic biotechnology to develop novel hybrid compounds for the agrochemical, pharmaceutical, cosmetic and chemistry sectors. Biosynthetic pathways of marine and extremophilic microorganisms will be reverse engineered to infer the individual roles of their constituent genes, which will be further combined for the production of non-natural biosurfactants and siderophores with tailor-made properties. Biosurfactants are compounds with surface-active nature tendency to adsorb at interfaces, while siderophores have the ability to chelate and transport Fe3+ ions. An iterative procedure following the Design-Build-Test-Learn methodological steps will be used to produce new microbial strains that support the selected genetic elements and satisfy sustainable industrial processing solutions for the production of biosurfactants and siderophores.
Keywords
Bioactive compounds;
Microbial communities;
Bioprospecting;
Bioproduct;
Drug discovery;
Human health;
Genetic;
Pharmaceuticals;
Cosmetics;
Engineering;
Genomic and gene mining;
Marine Region
76
Not associated to marine areas
0
Marine Region Map