Acronym ThermoFactories
Category
Marine Biotechnology
Title Thermophilic cell factories for efficient conversion of brown algae biomass to high-value chemicals Programme International Cooperation
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National-European Coordinator Trygve Brautaset Coordinator email trygve.brautaset@ntnu.no
Coordinator institution
NTNU - Norwegian University of Science and Technology (Norway)
Institutions involved
NA - Biotrend SA (Germany) ,
ULUND - Lund University (Sweden) ,
MATIS - Matis Ltd (Iceland) ,
NA - SilicoLife Lda (Portugal) ,
SINTEF MC - SINTEF Materials and Chemistry (Norway) ,
DTU - Technical University of Denmark (Denmark) ,
HI - University of Iceland (Iceland) ,
Start year 2016 End year 2018 Funding (€) € 2,485,677 Website https://www.vliz.be/projects/marinebiotech/thermophilic-cell-factories-efficient-conversion-brown-algae-biomass-high-value-chemicals.html Summary Brown algae biomass is a promising and challenging resource for industrial bioconversions, but there is a need to develop efficient cell factories to convert the constituent carbohydrates into high-value added products. In this proposal, four metabolically different environmental bacteria, inherently suitable to harsh process conditions, will be engineered for production of a number of industrially important platform and specialty chemicals, including 1,2-propanediol, cadaverine, propanol and lycopene. The project will implement and integrate systems biology and metabolic engineering, including rounds of model-driven metabolic optimization. Feedstock development and process engineering are important parts, to optimize fermentability of the algal hydrolysates, and ensure integration with downstream processing and product recovery. At the end of the project, use of all major carbohydrate Microbial metabolic engineering, systems fractions from brown algae through integrated processing will be demonstrated at small pilot scale.
Keywords
Bacteria;
Genetic;
Bioprocess;
Engineering;
Bioprospecting;
Marine Region
6
Central North Sea (27.IVb)
13
Northern North Sea (27.IVa)
5
Southern North Sea (27.IVc)
3
Marine Region Map
