Acronym CrispResist
Category
Marine Biotechnology
Title Harnessing cross-species variation in sea lice resistance Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Nicholas Andrew Robinson Coordinator email nick.robinson@nofima.no
Coordinator institution
NOFIMA - Norwegian Institute of Food, Fisheries and Aquaculture Research (Norway)
Institutions involved
NA - Bigelow Laboratory for Ocean Sciences (United States of America) ,
IMR - Institute of Marine Research (Norway) ,
UiB - University of Bergen (Norway) ,
NA - University of Edinburgh; Roslin Institute (United Kingdom) ,
UGOT - University of Gothenburg (Sweden) ,
UNIMELB - University of Melbourne (Australia) ,
UPEI - University of Prince Edward Island (Canada) ,
UoS-IOA - University of Stirling; Institute of Aquaculture (United Kingdom) ,
Start year 2020 End year 2025 Funding (€) € 3,839,820 Website https://www.fhf.no/prosjekter/prosjektbasen/901631/ Summary The project brings together researchers from Norway, the UK, the USA, Canada, Sweden and Australia to find the underlying mechanisms for species-independent variation in host resistance to the salmon louse Lepeophtheirus salmonis, and use this knowledge to strengthen resistance in Atlantic salmon. It has already been established that certain species of Pacific salmon are resistant to salmon lice and can defend themselves against lice at an early stage of parasitism, in contrast to Atlantic salmon which is very vulnerable to lice. The reason for the difference is primarily variation in the efficiency of the early immune response, but the louse's immunomodulation also appears to play a key role. A very promising but underutilized approach to salmon lice control is the improvement and development of the innate genetic resistance of the Atlantic salmon.
Main objective:
To elaborate and document the potential for utilizing genetic traits and mechanisms of salmon lice resistance in Pacific salmon as tools to achieve an Atlantic salmon with high or full salmon lice ( L. salmonis ) resistance.
Sub-objectives:
• To identify and document genes and mechanisms responsible for the difference in salmon lice resistance between salmonid species.
• To elaborate and document the potential for utilizing the identified genetic traits and mechanisms of salmon lice resistance as tools to achieve an Atlantic salmon with high or full salmon lice resistance.
• To conduct a risk evaluation on the possibilities for, and consequences of salmon lice adapting to Atlantic salmon with salmon lice resistance.
Keywords
Genomic sequencing;
Genetic;
Parasite;
Fish;
Salmon;
Engineering;
Marine Region
76
Not associated to marine areas
0
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