Acronym NA
Category
Marine Biotechnology
Title Growth hormone endocrinology in teleost fish: mechanisms of action and physiological functions Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Thrandur Björnsson Coordinator email Thrandur.Bjornsson@bioenv.gu.se
Coordinator institution
UGOT - University of Gothenburg (Sweden)
Institutions involved
NA
Start year 2006 End year 2008 Funding (€) € 8,800 Website NA Summary The growth hormone (GH) system in fish is the primary endocrine regulator of growth, and thus has complex effects on metabolism and energy balance. The system is pluripotent, regulating smoltification and hydromineral balance, and may have important regulatory roles during larval development and sexual maturation. A driving question is how a single hormone can exert such differentiated regulatory control. The research will focus on mechanisms of action by studying the growth hormone receptor and growth hormone binding proteins, as well as using a genome-wide microarray approach to identify genes affected by GH. Research on physiological function will focus on larval development and sexual maturation. These areas and approaches are of particular importance for both the fundamental and the applied understanding of GH endocrinology in fish. The knowledge will help solve aquaculture-related problems (abnormal development and early maturation), thus improving production and quality. An integrated physiology approach will utilize a range of methodologies including various experimental protocols, gene cloning, peptide purification and synthesis, antibody production, radioimmunoassays, immunohistochemistry, in situ hybridization, real-time quantitative PCR and microarrays. The project will be carried out by seven members of the Fish Endocrinology Laboratory, and is an essential, central part in an international collaborative network with research groups in Sweden, Europe and Canada.
Keywords
Fish biology;
Fish;
Genetic;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
