Acronym NA
Category
Aquaculture
Title Tracing viral disease dissemination in aquaculture: an interdisciplinary approach between molecular virology and dispersal modelling Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Peder Andreas Jansen Coordinator email peder.jansen@vetinst.no
Coordinator institution
NVI - Norwegian Veterinary Institute (Norway)
Institutions involved
NA
Start year 2008 End year 2009 Funding (€) € 380,907 Website https://www.fhf.no/prosjekter/prosjektbasen/900052/ Summary Viral diseases are a large problem in Norwegian salmon farming imposing economic as well as welfare-related challenges to the industry. In order to control the spread of viral diseases, knowledge on the transmission pathways of the disease agents and key factors affecting the interaction between the disease agent and the host, are vital. Molecular virological methods have proven useful for sensitive detection as well as genomic characterisation in studies on molecular epidemiology of important viral diseases, making use of phylogenitic analyses and identification of mutations important for virulence. Concomitantly, stochastic modelling of infectious diseases, and the spread of disease in aquaculture systems, is a developing field. The contribution from such models is that they may predict the space-time dynamics of disease dispersal. When disease dispersal is reasonably predicted, models can also be valuable as tools to simulate scenarios of importance to disease control or disease surveillance. However, model precision is critically dependent on knowledge of the biological and environmental factors that govern the development of host-pathogen interactions, and thus disease development. The present project proposal suggests an interdisciplinary approach of molecular virology and stochastic disease modelling to disentangle major transmission pathways of infectious salmon anaemia virus, and molecular characteristics of virus traits that may affect the probability of disease outbreaks.
Goal:
The aim of the project is to use kinship between gene sequences from the ISA virus to prove different transmission routes for the ISA virus.
To disentangle major transmission pathways for infectious salmon anemia virus (ISAV) in salmon farming, and ultimately develop more precise models for viral disease dispersal in salmon farming.
Sub-goals:
1. To base the studies on phylogeny and virulence of different strains of ISAV.
2. To initiate studies on the prevalence of non-virulent ISAV isolates circulating within farmed salmon populations, and the possible role of these in disease dissemination.
3. To utilize the phylogenetic relationships between virus isolates to assess model predictions regarding transmission pathways for ISAV.
4. To initiate the incorporation of molecular characteristics of virus isolates, eg. phylogeny, into disease dispersal models to ultimately increase model precision.
Keywords
Fish health;
Salmon;
Fish;
Disease;
Marine Region
76
Not associated to marine areas
0
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