Acronym NA
Category
Aquaculture
Title Resistance towards chemotherapeutants in Caligus species Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Celia Agusti Ridaura Coordinator email celia.agusti@nmbu.no
Coordinator institution
NMBU - Norwegian University of Life Sciences (Norway)
Institutions involved
NVH - Norwegian School of Veterinary Science (Norway) ,
Start year 2014 End year 2016 Funding (€) € 227,270 Website https://prosjektbanken.forskningsradet.no/en/project/FORISS/234060?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=30&ProgAkt.3=HAVBRUKS-Havbruk+-+en+n%C3%A6ring+i+vekst Summary Resistance in sea lice towards available treatments (pyrethroids, organophosphates and avermectins) is an increasing problem in Norwegian and international salmonid aquaculture. A considerable effort and good progress has been made on the salmon louse, Le peophtheirus salmonis, but little has been done regarding reduced sensitivity towards treatments in the parasitic copepods Caligus elongatus and C. rogercresseyi. The project will start with a bioassay surveillance of the sensitivity of C. elongatus towards the commonly used treatments against sea lice in Norwegian strains. If insensitivity is detected against one or more treatments, molecular methods will be used to amplify and sequence the genes coding for the target proteins in the search for mutations. Quantitative methods will be used to explore the expression levels of important detoxifying enzymes and other known resistance mechanisms in the parasites. If the mechanism(s) can be identified, rapid molecular assays can be developed, as is already the case for pyrethroid- and azamethiphos resistance in L. salmonis. In C. rogercresseyi, there is already ample evidence for resistance and this part of the project will focus on collecting representative samples for laboratory assays of mutations and expre ssion levels of known resistance mechanisms. The project will be integrated in the Sea Lice Research Centre, and performed at the Norwegian School of Veterinary Science. It will be a 2-year post doc project for Celia Agusti Ridaura.
Keywords
Fish;
Genetic;
Parasite;
Genomic sequencing;
Salmon;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
