Acronym NA
Category
Marine Biotechnology
Title Cartilage saccharides and bioactive compounds from sea cucumbers Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Olafur H. Fridjonsson Coordinator email olafur.h.fridjonsson@matis.is
Coordinator institution
MATIS - Matis Ltd (Iceland)
Institutions involved
NA - IceProtein (Iceland) ,
NA - Reykofninn Grundarfirði (Iceland) ,
HI - University of Iceland (Iceland) ,
Start year 2008 End year 2011 Funding (€) € 300,000 Website https://matis.is/en/matis_projects/cartilage-saccharides-and-bioactive-compounds-from-sea-cucumbers/ Summary "Chondroitin sulphate (CS) oligosaccharides are known to be valuable in terms of anti-cancer and anti-angiogenic activities. They show positive effects on digestion, inflammation, blood pressure, immune system, osteoarhritis, etc., and therefore, can be applied as medicine or food supplements. Chondroitin sulphate oligosaccharides can be produced with enzymatic digestion of CS polysaccharides from sea cucumbers which are a undeveloped species with a lot of exploitation opportunities. It has been shown that various types of sea cucumber possess different bioactive substances, which can be isolated and further processed. In this project, a process will be developed for production of chondroitin sulphate polysaccharides from cartilage of sea cucumbers and further, valuable oligosaccharides from enzyme digest of CS. Moreover, processing of bioactive extracts will be developed. Standardised products in terms of content and activity will be established. Demands and needs of markets for these products in Europe, Japan and Korea will be determined. The results of the project showed that it is possible to produce cartilage sugars from shark cartilage and coarsely refined cartilage sugars from simple edema. It is also possible to produce oligosaccharides from shark cartilage with specific biocatalysts.
The cartilage sugars show considerable bioactivity in vitro and cartilage sugars from Icelandic sea otters are particularly interesting as they show antioxidant activity, immune-regulating activity and hypoglycemic activity. "
Keywords
Bioprospecting;
Shellfish;
Market;
Bioactive compounds;
Echinoderm;
Sea cucumber;
Human health;
Marine Region
76
Not associated to marine areas
0
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