Acronym NA
Category
Marine Biotechnology
Title Karakterisering av virus assosiert med Hjertesprekk (CMS) og Hjerte- skjelettmuskel betennelse (HSMB) - Characterization of Viruses Associated with Cardiac Fracture (CMS) and Cardiovascular Inflammation (HSMB) Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Are Nylund Coordinator email are.nylund@bio.uib.no
Coordinator institution
UiB - University of Bergen (Norway)
Institutions involved
NA
Start year 2005 End year 2010 Funding (€) € 258,170 Website https://prosjektbanken.forskningsradet.no/en/project/FORISS/164832?Kilde=FORISS&Kilde=EU&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=4260<P.1=LTP2+Hav&source=FORISS&projectId=167795 Summary "Norwegian salmon farming is significantly affected by diseases with unclear causal factors, which pushes the industry's small profit margins in a negative direction. This group of diseases includes cardiac myopathy syndrome (CMS), haemorrhagic smolt syndrome (HSS) and myocardial infarction (HSMB). The losses associated with these diseases range from less than 1% (HSS) and up to 70% (CMS). It has also been shown that even though HSMB only gives up to 10% mortality in production facilities, 100% of the population in the facility may be affected by the disease. Preliminary studies at our laboratory indicate that all three diseases can be caused by viruses and a number of viruses from salmon with these diseases have been detected by transmission electron microscopy. However, it is not clear if there is a causal link between these viruses and the diseases themselves. However, CMS and HSMB can be transmitted in infection trials on fresh salmon.
Today's diagnostics (based on clinical signs and histology) can only detect terminally ill individuals (not carriers), and that CMS can be a collective term for a number of diseases (where, among other things, salmon pancreatic disease virus, SPDV, may be involved.). Future prevention and control of CMS and HSMB presupposes better knowledge of causation and transmission mechanisms, both of which presuppose specific and sensitive diagnostic tools, ie that agents can be identified. Furthermore, knowledge of the genome from the various agents will be a prerequisite for the development of vaccines. The main goal of the project is therefore to identify and characterize (morphological and molecular) agents associated with CMS and HSMB."
Keywords
Salmon;
Genetic;
Fish;
Disease;
Biology;
Marine Region
76
Not associated to marine areas
0
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