Acronym SWAFAX
Category
Marine Biotechnology
Title Seaweed Derivied Anti-inflammatory Agents and Antioxidants Programme FP7
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
FP7 - Research for SMEs
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
SME – Research for the benefit of SMEs
Specific Programme (FP7)
Capacities
Funding source European Coordinator NA Coordinator email NA
Coordinator institution
NA
Institutions involved
NA - Cybercolloids Ltd (Ireland) ,
NA - Hebridean Seaweed Company Ltd (United Kingdom) ,
NA - Marigot Ltd (Ireland) ,
NA - MesoSystem SL (Spain) ,
NA - University of Ulster (United Kingdom) ,
Start year 2010 End year 2013 Funding (€) € 1,331,399 Website https://cordis.europa.eu/project/id/262519 Summary The project is designed to address a commercial opportunity to obtain bioactive compounds from seaweeds for application in food and health & wellness products. Although polyphenols from land plants are widely used as functional food ingredients and food supplements, seaweed sources have been little studied or exploited. The consortium comprises 4 SME partners Hebridean Seaweed, Marigot, Coressence and Mesosystem, and 3 RTD providers – CyberColloids and Universities of Reading and Ulster. In the first stage of the project seaweed polyphenol extracts (SPEs) will be prepared. One of the SPEs will be produced at food grade quality from Ascophyllum. In addition, a series of novel polyphenol extracts from a range of seaweed types of relevance to the partner SMEs, will be prepared. All the extracts will be characterised for their polyphenol content. The antioxidant and anti-inflammatory activities of the food grade SPE will be assessed in a dietary intervention trial in human subjects. The end points will include prevention of oxidative DNA damage in lymphocytes, and modulation of anti-inflammatory and pro-inflammatory cytokines in plasma. In addition a short-term dietary intervention in human volunteers will be conducted to assess bioavailability and metabolism of the component polyphenols in the extract. Finally the novel SPEs will be investigated for anti-inflammatory and anti oxidant activity in vitro. The food grade SPE will be included as a comparator. In this way it should be possible to extrapolate from the in vitro activities to provide an estimate of the likely in vivo effects in terms of anti-oxidant and anti-inflammatory properties and to provide the SME’s with candidate extracts with potential beneficial properties that can be further developed at a later stage. The SME partners in conjunction with Cybercolloids will implement polyphenol extract technology transfer and formulate a route to market
Keywords
Bioactive compounds;
Biomaterial;
Human health;
Algae;
Bioprospecting;
Marine Region
76
Not associated to marine areas
0
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