Acronym NA
Category
Aquaculture
Title Seafood Risk-benefit Methylmercury and nutrient interactions in the development of life style diseases Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Lise Madsen Coordinator email lise.madsen@nifes.no
Coordinator institution
NIFES - National Institute of Nutrition and Seafood Research (Norway)
Institutions involved
NA
Start year 2013 End year 2018 Funding (€) € 1,704,700 Website https://prosjektbanken.forskningsradet.no/en/project/FORISS/228892?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=150&TemaEmne.2=Fiskeri Summary This project will contribute to decrease the knowledge gaps identified in the recent risk-benefit evaluation of seafood (FAO/WHO, 2011) related to methylmercury (MeHg) and seafood nutrients interactions in the development and progression of non-communicab le diseases. Mercury is a globally dispersed contaminant, and despite efforts to limit environmental contamination by a number of countries, mercury contamination of seafood will continue. Methylmercury, the organic form of mercury accumulate the the aqua tic food chain and represent a potential health risk for the consumers. Marine omega-3 fatty acids (EPA; 20:5n-3 and DHA; 22:6n-3) have been reported to be beneficial where MeHg is reported to be detrimental. For instance, marine omega-3 fatty acid protec t against whereas MeHg is suggested to contribute to development of certain neurological and cardiovascular diseases. In addition to marine omega-3 fatty acids, selenium (Se) may ameliorate toxicity through binding to MeHg and thereby reducing its bioavai lability and biological activity. Therefore, the current project will aim to increase the knowledge on impact of MeHg on development and progression cardiovascular disease (CVD) and neuro-degenerative disorders (NDD) and explore the underlying mechanisms. Furthermore, the possible role of MeHg on other of life style diseases, such as obesity and type-2 diabetes (T2D) will be investigated. Basic molecular mechanisms being affected by MeHg and marine omega-3 fatty acids, seafood proteins or selenium will be studied to improve understanding of MeHg toxic effects and possible ameliorating effects of seafood nutrients. The knowledge obtained through this project will contribute to future risk benefit evaluations of methylmercury and seafood nutrients.
Keywords
Food safety;
Toxic substances;
Impacts;
Marine Region
76
Not associated to marine areas
0
Marine Region Map
