Acronym NA
Category
Marine Biotechnology
Title Antimicrobial peptides and proteins mediating viral defense in Atlantic salmon Programme National Programme
Instrument (FP6)
Contact Type (FP7)
Strand (Interreg)
NA
Theme (FP7)
Activity Area (FP6)
Regional Area (Interreg)
Action (COST)
NA
Specific Programme (FP7)
NA
Funding source National Coordinator Yoichiro Kitani Coordinator email NA
Coordinator institution
NA
Institutions involved
NA - INNOVAOLEO SL
(Spain) ,
Start year 2014 End year 2016 Funding (€) € 227,270 Website https://prosjektbanken.forskningsradet.no/en/project/FORISS/233884?Kilde=FORISS&distribution=Ar&chart=bar&calcType=funding&Sprak=no&sortBy=date&sortOrder=desc&resultCount=30&offset=300&ProgAkt.3=HAVBRUK2-Stort+program+for+havbruksforskning Summary Atlantic salmon farming industry in Norway registered mortality of 27 million in 2012 and viral diseases such as infectious salmon anaemia, pancreas disease, heart and skeletal muscle inflammation, cardiomyopathy syndrome and infectious pancreatic necrosis continue to plague the industry. To combat diseases, new and sustainable solutions should be discovered. A possible choice could be to exploit the molecules of the innate immune system, including antimicrobial peptides and proteins (AMPs). Therefore, the present project aims to understand the antiviral potential of selected AMPs of Atlantic salmon. Molecular and biochemical approaches will be employed to clarify the functions and structure of the chosen AMPs - defensin, cathelicidin and L-amino acid oxidase. Their action in naturally and experimentally infected Atlantic salmon would be investigated. The antiviral properties of the recombinant AMPs against a range of viruses will be assessed in vitro. The knowledge on the antiviral capabilities of the AMPs would be valuable in the future to develop them as disease control agents.
Keywords
Fish;
Bioactive compounds;
Salmon;
Byproducts;
Fish health;
Animal feed;
Waste valorization;
Bioprospecting;
Animal welfare;
Marine Region
52
Northern Alboran Sea (GSA 1)
1
Marine Region Map
